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Chapter 2. Standards And Schedules of California Health And Safety Code >> Division 10. >> Chapter 2.

The controlled substances listed or to be listed in the schedules in this chapter are included by whatever official, common, usual, chemical, or trade name designated.
(a) The controlled substances listed in this section are included in Schedule I.
  (b) Opiates. Unless specifically excepted or unless listed in another schedule, any of the following opiates, including their isomers, esters, ethers, salts, and salts of isomers, esters, and ethers whenever the existence of those isomers, esters, ethers, and salts is possible within the specific chemical designation:
  (1) Acetylmethadol.
  (2) Allylprodine.
  (3) Alphacetylmethadol (except levoalphacetylmethadol, also known as levo-alpha- acetylmethadol, levomethadyl acetate, or LAAM).
  (4) Alphameprodine.
  (5) Alphamethadol.
  (6) Benzethidine.
  (7) Betacetylmethadol.
  (8) Betameprodine.
  (9) Betamethadol.
  (10) Betaprodine.
  (11) Clonitazene.
  (12) Dextromoramide.
  (13) Diampromide.
  (14) Diethylthiambutene.
  (15) Difenoxin.
  (16) Dimenoxadol.
  (17) Dimepheptanol.
  (18) Dimethylthiambutene.
  (19) Dioxaphetyl butyrate.
  (20) Dipipanone.
  (21) Ethylmethylthiambutene.
  (22) Etonitazene.
  (23) Etoxeridine.
  (24) Furethidine.
  (25) Hydroxypethidine.
  (26) Ketobemidone.
  (27) Levomoramide.
  (28) Levophenacylmorphan.
  (29) Morpheridine.
  (30) Noracymethadol.
  (31) Norlevorphanol.
  (32) Normethadone.
  (33) Norpipanone.
  (34) Phenadoxone.
  (35) Phenampromide.
  (36) Phenomorphan.
  (37) Phenoperidine.
  (38) Piritramide.
  (39) Proheptazine.
  (40) Properidine.
  (41) Propiram.
  (42) Racemoramide.
  (43) Tilidine.
  (44) Trimeperidine.
  (45) Any substance which contains any quantity of acetylfentanyl (N-[1-phenethyl-4-piperidinyl] acetanilide) or a derivative thereof.
  (46) Any substance which contains any quantity of the thiophene analog of acetylfentanyl (N-[1-[2-(2-thienyl)ethyl]-4-piperidinyl] acetanilide) or a derivative thereof.
  (47) 1-Methyl-4-Phenyl-4-Propionoxypiperidine (MPPP).
  (48) 1-(2-Phenethyl)-4-Phenyl-4-Acetyloxypiperidine (PEPAP).
  (c) Opium derivatives. Unless specifically excepted or unless listed in another schedule, any of the following opium derivatives, its salts, isomers, and salts of isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation:
  (1) Acetorphine.
  (2) Acetyldihydrocodeine.
  (3) Benzylmorphine.
  (4) Codeine methylbromide.
  (5) Codeine-N-Oxide.
  (6) Cyprenorphine.
  (7) Desomorphine.
  (8) Dihydromorphine.
  (9) Drotebanol.
  (10) Etorphine (except hydrochloride salt).
  (11) Heroin.
  (12) Hydromorphinol.
  (13) Methyldesorphine.
  (14) Methyldihydromorphine.
  (15) Morphine methylbromide.
  (16) Morphine methylsulfonate.
  (17) Morphine-N-Oxide.
  (18) Myrophine.
  (19) Nicocodeine.
  (20) Nicomorphine.
  (21) Normorphine.
  (22) Pholcodine.
  (23) Thebacon.
  (d) Hallucinogenic substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation, which contains any quantity of the following hallucinogenic substances, or which contains any of its salts, isomers, and salts of isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation (for purposes of this subdivision only, the term "isomer" includes the optical, position, and geometric isomers):
  (1) 4-bromo-2,5-dimethoxy-amphetamine--Some trade or other names: 4-bromo-2,5-dimethoxy-alpha-methylphenethylamine; 4-bromo-2,5-DMA.
  (2) 2,5-dimethoxyamphetamine--Some trade or other names: 2,5-dimethoxy-alpha-methylphenethylamine; 2,5-DMA.
  (3) 4-methoxyamphetamine--Some trade or other names: 4-methoxy-alpha-methylphenethylamine, paramethoxyamphetamine, PMA.
  (4) 5-methoxy-3,4-methylenedioxy-amphetamine.
  (5) 4-methyl-2,5-dimethoxy-amphetamine--Some trade or other names: 4-methyl-2,5-dimethoxy-alpha-methylphenethylamine; "DOM"; and "STP."
  (6) 3,4-methylenedioxy amphetamine.
  (7) 3,4,5-trimethoxy amphetamine.
  (8) Bufotenine--Some trade or other names: 3- (beta-dimethylaminoethyl)-5-hydroxyindole; 3-(2-dimethylaminoethyl)-5 indolol; N,N-dimethylserolonin, 5-hydroxy-N,N-dimethyltryptamine; mappine.
  (9) Diethyltryptamine--Some trade or other names: N,N-Diethyltryptamine; DET.
  (10) Dimethyltryptamine--Some trade or other names: DMT.
  (11) Ibogaine--Some trade or other names: 7-Ethyl-6,6beta, 7,8,9,10,12,13-octahydro-2-methoxy-6,9-methano-5H-pyrido [1',2':1,2] azepino [5,4-b] indole; Tabernantheiboga.
  (12) Lysergic acid diethylamide.
  (13) Marijuana.
  (14) Mescaline.
  (15) Peyote--Meaning all parts of the plant presently classified botanically as Lophophora williamsii Lemaire, whether growing or not, the seeds thereof, any extract from any part of the plant, and every compound, manufacture, salts, derivative, mixture, or preparation of the plant, its seeds or extracts (interprets 21 U.S.C. Sec. 812(c), Schedule 1(c)(12)).
  (16) N-ethyl-3-piperidyl benzilate.
  (17) N-methyl-3-piperidyl benzilate.
  (18) Psilocybin.
  (19) Psilocyn.
  (20) Tetrahydrocannabinols. Synthetic equivalents of the substances contained in the plant, or in the resinous extractives of Cannabis, sp. and/or synthetic substances, derivatives, and their isomers with similar chemical structure and pharmacological activity such as the following: delta 1 cis or trans tetrahydrocannabinol, and their optical isomers; delta 6 cis or trans tetrahydrocannabinol, and their optical isomers; delta 3,4 cis or trans tetrahydrocannabinol, and its optical isomers.
  (Since nomenclature of these substances is not internationally standardized, compounds of these structures, regardless of numerical designation of atomic positions covered).
  (21) Ethylamine analog of phencyclidine--Some trade or other names: N-ethyl-1-phenylcyclohexylamine, (1-phenylcyclohexyl) ethylamine, N-(1-phenylcyclohexyl) ethylamine, cyclohexamine, PCE.
  (22) Pyrrolidine analog of phencyclidine--Some trade or other names: 1-(1-phenylcyclohexyl)-pyrrolidine, PCP, PHP.
  (23) Thiophene analog of phencyclidine--Some trade or other names: 1-[1-(2 thienyl)-cyclohexyl]-piperidine, 2-thienyl analog of phencyclidine, TPCP, TCP.
  (e) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation:
  (1) Mecloqualone.
  (2) Methaqualone.
  (3) Gamma hydroxybutyric acid (also known by other names such as GHB; gamma hydroxy butyrate; 4-hydroxybutyrate; 4-hydroxybutanoic acid; sodium oxybate; sodium oxybutyrate), including its immediate precursors, isomers, esters, ethers, salts, and salts of isomers, esters, and ethers, including, but not limited to, gammabutyrolactone, for which an application has not been approved under Section 505 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. Sec. 355).
  (f) Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its isomers:
  (1) Cocaine base.
  (2) Fenethylline, including its salts.
  (3) N-Ethylamphetamine, including its salts.
(a) The controlled substances listed in this section are included in Schedule II.
  (b) Any of the following substances, except those narcotic drugs listed in other schedules, whether produced directly or indirectly by extraction from substances of vegetable origin, or independently by means of chemical synthesis, or by combination of extraction and chemical synthesis:
  (1) Opium, opiate, and any salt, compound, derivative, or preparation of opium or opiate, with the exception of naloxone hydrochloride (N-allyl-14-hydroxy-nordihydromorphinone hydrochloride), but including the following:
  (A) Raw opium.
  (B) Opium extracts.
  (C) Opium fluid extracts.
  (D) Powdered opium.
  (E) Granulated opium.
  (F) Tincture of opium.
  (G) Codeine.
  (H) Ethylmorphine.
  (I) Hydrocodone.
  (J) Hydromorphone.
  (K) Metopon.
  (L) Morphine.
  (M) Oxycodone.
  (N) Oxymorphone.
  (O) Thebaine.
  (2) Any salt, compound, isomer, or derivative, whether natural or synthetic, of the substances referred to in paragraph (1), but not including the isoquinoline alkaloids of opium.
  (3) Opium poppy and poppy straw.
  (4) Coca leaves and any salt, compound, derivative, or preparation of coca leaves, but not including decocainized coca leaves or extractions which do not contain cocaine or ecgonine.
  (5) Concentrate of poppy straw (the crude extract of poppy straw in either liquid, solid, or powder form which contains the phenanthrene alkaloids of the opium poppy).
  (6) Cocaine, except as specified in Section 11054.
  (7) Ecgonine, whether natural or synthetic, or any salt, isomer, derivative, or preparation thereof.
  (c) Opiates. Unless specifically excepted or unless in another schedule, any of the following opiates, including its isomers, esters, ethers, salts, and salts of isomers, esters, and ethers whenever the existence of those isomers, esters, ethers, and salts is possible within the specific chemical designation, dextrorphan and levopropoxyphene excepted:
  (1) Alfentanyl.
  (2) Alphaprodine.
  (3) Anileridine.
  (4) Bezitramide.
  (5) Bulk dextropropoxyphene (nondosage forms).
  (6) Dihydrocodeine.
  (7) Diphenoxylate.
  (8) Fentanyl.
  (9) Isomethadone.
  (10) Levoalphacetylmethadol, also known as levo-alpha-acetylmethadol, levomethadyl acetate, or LAAM. This substance is authorized for the treatment of narcotic addicts under federal law (see Part 291 (commencing with Section 291.501) and Part 1308 (commencing with Section 1308.01) of Title 21 of the Code of Federal Regulations).
  (11) Levomethorphan.
  (12) Levorphanol.
  (13) Metazocine.
  (14) Methadone.
  (15) Methadone-Intermediate, 4-cyano-2-dimethylamino-4, 4-diphenyl butane.
  (16) Moramide-Intermediate, 2-methyl-3-morpholino-1, 1-diphenylpropane-carboxylic acid.
  (17) Pethidine (meperidine).
  (18) Pethidine-Intermediate-A, 4-cyano-1-methyl-4-phenylpiperidine.
  (19) Pethidine-Intermediate-B, ethyl-4-phenylpiperidine-4-carboxylate.
  (20) Pethidine-Intermediate-C, 1-methyl-4-phenylpiperidine-4-carboxylic acid.
  (21) Phenazocine.
  (22) Piminodine.
  (23) Racemethorphan.
  (24) Racemorphan.
  (25) Sufentanyl.
  (d) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system:
  (1) Amphetamine, its salts, optical isomers, and salts of its optical isomers.
  (2) Methamphetamine, its salts, isomers, and salts of its isomers.
  (3) Dimethylamphetamine (N,N-dimethylamphetamine), its salts, isomers, and salts of its isomers.
  (4) N-Ethylmethamphetamine (N-ethyl, N-methylamphetamine), its salts, isomers, and salts of its isomers.
  (5) Phenmetrazine and its salts.
  (6) Methylphenidate.
  (7) Khat, which includes all parts of the plant classified botanically as Catha Edulis, whether growing or not, the seeds thereof, any extract from any part of the plant, and every compound, manufacture, salt, derivative, mixture, or preparation of the plant, its seeds, or extracts.
  (8) Cathinone (also known as alpha-aminopropiophenone, 2-aminopropiophenone, and norephedrone).
  (e) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system, including its salts, isomers, and salts of isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation:
  (1) Amobarbital.
  (2) Pentobarbital.
  (3) Phencyclidines, including the following:
  (A) 1-(1-phenylcyclohexyl) piperidine (PCP).
  (B) 1-(1-phenylcyclohexyl) morpholine (PCM).
  (C) Any analog of phencyclidine which is added by the Attorney General by regulation pursuant to this paragraph. The Attorney General, or his or her designee, may, by rule or regulation, add additional analogs of phencyclidine to those enumerated in this paragraph after notice, posting, and hearing pursuant to Chapter 3.5 (commencing with Section 11340) of Part 1 of Division 3 of Title 2 of the Government Code. The Attorney General shall, in the calendar year of the regular session of the Legislature in which the rule or regulation is adopted, submit a draft of a proposed bill to each house of the Legislature which would incorporate the analogs into this code. No rule or regulation shall remain in effect beyond January 1 after the calendar year of the regular session in which the draft of the proposed bill is submitted to each house. However, if the draft of the proposed bill is submitted during a recess of the Legislature exceeding 45 calendar days, the rule or regulation shall be effective until January 1 after the next calendar year.
  (4) Secobarbital.
  (5) Glutethimide.
  (f) Immediate precursors. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances:
  (1) Immediate precursor to amphetamine and methamphetamine:
  (A) Phenylacetone. Some trade or other names: phenyl-2 propanone; P2P; benzyl methyl ketone; methyl benzyl ketone.
  (2) Immediate precursors to phencyclidine (PCP):
  (A) 1-phenylcyclohexylamine.
  (B) 1-piperidinocyclohexane carbonitrile (PCC).
(a) The controlled substances listed in this section are included in Schedule III.
  (b) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers (whether optical, position, or geometric), and salts of those isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation:
  (1) Those compounds, mixtures, or preparations in dosage unit form containing any stimulant substances listed in Schedule II which compounds, mixtures, or preparations were listed on August 25, 1971, as excepted compounds under Section 1308.32 of Title 21 of the Code of Federal Regulations, and any other drug of the quantitative composition shown in that list for those drugs or which is the same except that it contains a lesser quantity of controlled substances.
  (2) Benzphetamine.
  (3) Chlorphentermine.
  (4) Clortermine.
  (5) Mazindol.
  (6) Phendimetrazine.
  (c) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a depressant effect on the central nervous system:
  (1) Any compound, mixture, or preparation containing any of the following:
  (A) Amobarbital
  (B) Secobarbital
  (C) Pentobarbital or any salt thereof and one or more other active medicinal ingredients which are not listed in any schedule.
  (2) Any suppository dosage form containing any of the following:
  (A) Amobarbital
  (B) Secobarbital
  (C) Pentobarbital or any salt of any of these drugs and approved by the federal Food and Drug Administration for marketing only as a suppository.
  (3) Any substance which contains any quantity of a derivative of barbituric acid or any salt thereof.
  (4) Chlorhexadol.
  (5) Lysergic acid.
  (6) Lysergic acid amide.
  (7) Methyprylon.
  (8) Sulfondiethylmethane.
  (9) Sulfonethylmethane.
  (10) Sulfonmethane.
  (11) Gamma hydroxybutyric acid, and its salts, isomers and salts of isomers, contained in a drug product for which an application has been approved under Section 505 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C. Sec. 355).
  (d) Nalorphine.
  (e) Narcotic drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as set forth below:
  (1) Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with an equal or greater quantity of an isoquinoline alkaloid of opium.
  (2) Not more than 1.8 grams of codeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts.
  (3) Not more than 300 milligrams of dihydrocodeinone per 100 milliliters or not more than 15 milligrams per dosage unit, with a fourfold or greater quantity of an isoquinoline alkaloid of opium.
  (4) Not more than 300 milligrams of dihydrocodeinone per 100 milliliters or not more than 15 milligrams per dosage unit, with one or more active nonnarcotic ingredients in recognized therapeutic amounts. Additionally, oral liquid preparations of dihydrocodeinone containing the above specified amounts may not contain as its nonnarcotic ingredients two or more antihistamines in combination with each other.
  (5) Not more than 1.8 grams of dihydrocodeine per 100 milliliters or not more than 90 milligrams per dosage unit, with one or more active nonnarcotic ingredients in recognized therapeutic amounts.
  (6) Not more than 300 milligrams of ethylmorphine per 100 milliliters or not more than 15 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts.
  (7) Not more than 500 milligrams of opium per 100 milliliters or per 100 grams or not more than 25 milligrams per dosage unit, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts.
  (8) Not more than 50 milligrams of morphine per 100 milliliters or per 100 grams, with one or more active, nonnarcotic ingredients in recognized therapeutic amounts.
  (f) Anabolic steroids and chorionic gonadotropin. Any material, compound, mixture, or preparation containing chorionic gonadotropin or an anabolic steroid (excluding anabolic steroid products listed in the "Table of Exempt Anabolic Steroid Products" (Section 1308.34 of Title 21 of the Code of Federal Regulations), as exempt from the federal Controlled Substances Act (Section 801 and following of Title 21 of the United States Code)), including, but not limited to, the following:
  (1) Androisoxazole.
  (2) Androstenediol.
  (3) Bolandiol.
  (4) Bolasterone.
  (5) Boldenone.
  (6) Chlormethandienone.
  (7) Clostebol.
  (8) Dihydromesterone.
  (9) Ethylestrenol.
  (10) Fluoxymesterone.
  (11) Formyldienolone.
  (12) 4-Hydroxy-19-nortestosterone.
  (13) Mesterolone.
  (14) Methandriol.
  (15) Methandrostenolone.
  (16) Methenolone.
  (17) 17-Methyltestosterone.
  (18) Methyltrienolone.
  (19) Nandrolone.
  (20) Norbolethone.
  (21) Norethandrolone.
  (22) Normethandrolone.
  (23) Oxandrolone.
  (24) Oxymestrone.
  (25) Oxymetholone.
  (26) Quinbolone.
  (27) Stanolone.
  (28) Stanozolol.
  (29) Stenbolone.
  (30) Testosterone.
  (31) Trenbolone.
  (32) Chorionic Gonadotropin (HGC).
  (g) Ketamine. Any material, compound, mixture, or preparation containing ketamine.
  (h) Hallucinogenic substances. Any of the following hallucinogenic substances: dronabinol (synthetic) in sesame oil and encapsulated in a soft gelatin capsule in a drug product approved by the federal Food and Drug Administration.
(a) The controlled substances listed in this section are included in Schedule IV.
  (b) Schedule IV shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section.
  (c) Narcotic drugs. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as set forth below:
  (1) Not more than 1 milligram of difenoxin and not less than 25 micrograms of atropine sulfate per dosage unit.
  (2) Dextropropoxyphene (alpha-(+)-4-dimethylamino-1, 2-diphenyl-3-methyl-2-propionoxybutane).
  (3) Butorphanol.
  (d) Depressants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers, and salts of isomers whenever the existence of those salts, isomers, and salts of isomers is possible within the specific chemical designation:
  (1) Alprazolam.
  (2) Barbital.
  (3) Chloral betaine.
  (4) Chloral hydrate.
  (5) Chlordiazepoxide.
  (6) Clobazam.
  (7) Clonazepam.
  (8) Clorazepate.
  (9) Diazepam.
  (10) Estazolam.
  (11) Ethchlorvynol.
  (12) Ethinamate.
  (13) Flunitrazepam.
  (14) Flurazepam.
  (15) Halazepam.
  (16) Lorazepam.
  (17) Mebutamate.
  (18) Meprobamate.
  (19) Methohexital.
  (20) Methylphenobarbital (Mephobarbital).
  (21) Midazolam.
  (22) Nitrazepam.
  (23) Oxazepam.
  (24) Paraldehyde.
  (25) Petrichoral.
  (26) Phenobarbital.
  (27) Prazepam.
  (28) Quazepam.
  (29) Temazepam.
  (30) Triazolam.
  (31) Zaleplon.
  (32) Zolpidem.
  (e) Fenfluramine. Any material, compound, mixture, or preparation which contains any quantity of the following substances, including its salts, isomers (whether optical, position, or geometric), and salts of those isomers, whenever the existence of those salts, isomers, and salts of isomers is possible:
  (1) Fenfluramine.
  (f) Stimulants. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture, or preparation which contains any quantity of the following substances having a stimulant effect on the central nervous system, including its salts, isomers (whether optical, position, or geometric), and salts of those isomers is possible within the specific chemical designation:
  (1) Diethylpropion.
  (2) Mazindol.
  (3) Modafinil.
  (4) Phentermine.
  (5) Pemoline (including organometallic complexes and chelates thereof).
  (6) Pipradrol.
  (7) SPA ((-)-1-dimethylamino-1,2-diphenylethane).
  (8) Cathine ((+)-norpseudoephedrine).
  (g) Other substances. Unless specifically excepted or unless listed in another schedule, any material, compound, mixture or preparation which contains any quantity of pentazocine, including its salts.
(a) The controlled substances listed in this section are included in Schedule V.
  (b) Schedule V shall consist of the drugs and other substances, by whatever official name, common or usual name, chemical name, or brand name designated, listed in this section.
  (c) Narcotic drugs containing nonnarcotic active medicinal ingredients. Any compound, mixture, or preparation containing any of the following narcotic drugs, or their salts calculated as the free anhydrous base or alkaloid, in limited quantities as set forth below, which shall include one or more nonnarcotic active medicinal ingredients in sufficient proportion to confer upon the compound, mixture, or preparation valuable medicinal qualities other than those possessed by narcotic drugs alone:
  (1) Not more than 200 milligrams of codeine per 100 milliliters or per 100 grams.
  (2) Not more than 100 milligrams of dihydrocodeine per 100 milliliters or per 100 grams.
  (3) Not more than 100 milligrams of ethylmorphine per 100 milliliters or per 100 grams.
  (4) Not more than 2.5 milligrams of diphenoxylate and not less than 25 micrograms of atropine sulfate per dosage unit.
  (5) Not more than 100 milligrams of opium per 100 milliliters or per 100 grams.
  (6) Not more than 0.5 milligram of difenoxin and not less than 25 micrograms of atropine sulfate per dosage unit.
  (d) Buprenorphine.